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RGUHS Nat. J. Pub. Heal. Sci Vol No: 11 Issue No: 2  pISSN: 2249-2194

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INQUISITIVE UNDERSTANDING OF SAMPRAPTI VIGHATANA IN PRIMARY HYPOTHYROIDISM WITH OBESITY AS A RASAPRADOSHAJA VIKARA

Dr Shruthi Shivarama*, Dr Mythrey R C

SDM Institute of Ayurveda and Hospital Bengaluru India.
Thyroid gland is an essential endocrine gland, which plays a major role in chemical reactions in the body (maintaining basal metabolic rate), as well as growth and development. It is located in the neck region where Vishuddha chakra resides. Primary hypothyroidism or overt hypothyroidism is a condition where there is elevated thyroid stimulating hormone (TSH) >10 mU/L with free t4 level below the normal range exhibiting features like weight gain, dry skin, cold intolerance, depression etc. Aharaja, Viharaja, Manasika and Jatajanya nidana’s are acting as a moola karana in vyadhi utpatti. Which makes Kapha, Vata vruddhi and Pitta kshaya leading to Agni vaishamyata (Jatharagni), Rasa and Medho dhatvagni vyatyasa causing Primary hypothyroidism with Obesity. Ayurveda Chikitsa focus on Nidana parivarjana, Samshodhana, Samshamana, proper implementation of Dinacharya and Pathya Apathya. This eventually increases Agni bala, balance the tridosha and manages the Rasa and Medo dhatu functions and helps in managing the Vyadhi. The prognosis of the disease has a wider impact on other system like respiratory, cardiac, gastrointestinal, metabolic, skin, renal and musculoskeletal systems exhibiting various clinical features. Reviewing the literatures it was found that Primary hypothyroidism and Obesity has an intriguing link. Hence it is the need of the hour and an attempt is made to strategically interpret and analyse the concepts for the proper management.

A randomized controlled open labelled parallel group clinical study to evaluate the efficacy of Chitraka granthikadi kashaya in the management of constipation.

Dr Dhanya PR

Sri sri college of ayurvedic science and research
Background:- Constipation is one of the most common gastro intestinal disease. The contemporary management with laxatives has various drawbacks. Thus a randomized controlled trial was designed with an Ayurvedic poly herbal formulation in comparison with a control group. Objective:- The study was conducted to evaluate the efficacy of an Ayurvedic poly herbal formulation, Chitrakagranthikadi kashaya in the management of clinically diagnosed primary constipation. Materials and Methods:- The current study was a prospective, randomized, open labelled, active controlled, parallel group clinical study with pre and post test design. It was conducted at SSCASR-Bangalore, Karnataka between May-2021 to May-2022. A computer generated table (block) randomization technique was adopted. The total 30 subjects, aged 21-65years diagnosed with constipation were assigned into 2 groups; Intervention [A] group n=15, received the control drug isabgol husk powder 3.5 gm, twice daily, after food and group [B] n=15 received trial drug Chitraka granthikadi kashaya 50ml twice daily before food for 20 days. Subjective parameters were assessed based on the assessment criteria at baseline, 20th day and drug free follow-up on 27th day. Observations and Results:- The trial status is completed with 30 subjects [no dropouts]. Both groups were showed clinically significant for the subjective parameters. Conclusion :-A statistically significant result was obtained in both the groups. But Chitraka granthikadi kashaya reduced the incidence of constipation with a persistant effect. Keywords :- Ayurveda, Chitraka granthikadi kashaya , Constipation, Isabgol husk powder, Randomized control trial.

THE COMBINED EFFECT OF SHATAVARI GHRITA TARPANA AND EYE EXERCISES IN PRATAMA PATALAGATA TIMIRA WITH SPECIAL REFERENCE TO SIMPLE MYOPIA - "CASE REPORT"

Mohana Kumari, Dr.Syed Munwer Pasha

GAMC BENGALURU India.
INTRODUCTION : Simple myopia, commonly referred to as near sightedness, is a prevalent refractive error affecting millions worldwide. signs and symptoms of Simple Myopia can be equated with the lakshanas of Prathama patalagata Timira.It is one among the drishtigata netra rogas . Avyakta darshana (Impairement in vision) is the main lakshana mentioned under prathama patalagata timira. Simple myopia is the most common refractive error seen in young children and adults. This case study delves into the management of simple myopia of a 21 year-old individual presenting with blurred distant vision in both eye. The subject who approached Shalakya Tantra OPD GAMC Bengaluru with lakshana’s of pratama patalagata timira was thouroughly examined, systematically reviewed and managed with Tarpana with Shatavari Ghrita and Eye Exercises. The patient showed considerable improvement subjectively and objectively. Improvement in Visual Acuity and autorefraction was observed in both eyes. Simple myopia is a common refractive error with significant implications for daily functioning and quality of life. In this study, Tarpana with Shatavari Ghrita and Eye Exercises has shown significant improvement in simple myopia.

Critical analysis of Shilajatu in Diabetic peripheral Neuropathy- Review article

Rakesh Moolya, Dr Mythrey R C

Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital Hassan
Diabetic peripheral neuropathy (DPN) is the most prevalent consequence of diabetes mellitus (DM). The conventional system's inability to provide adequate therapy causes the disease to worsen, which may result in nontraumatic amputation and neuropathic condition. Purvarupa and Prameha Janya Upadrava are two broad headings that can be used to compare the symptomatology that corresponds to the clinical presentation of DPN as it arises due to DM. Vataja nanatmaja vikaras deals with additional lakshanas such as Pada supti and Padaharsha. The concept of Avarana Vata helps in understanding the condition better. If the drug possesses Rasayana property, it will be an added advantage. Shilajatu (Asphalthum punjabianum) is laghu, sheeta virya, katu vipaka and anamla panchrasa. Its katu vipaka makes it a srotosodhaka, which clears the microchannels. with these attributes Shilajatu aids with dosha pachana (toxic metabolites), eliminates avrana and srotoshodhana. It pacifies vata and prevents the deterioration of nerve tissue. Shilajatu's ojovardhana property assures Dhatu poshana (at the cellular level), which in turn may promote nerve cell regeneration. Further experimental studies have shown Fulvic acid present in shilajatu reduces the risks of degeneration. Further shilajatu is a rasayana for prameha and also a rasayana for vata vyadhi. Hence due to above all the qualities shilajatu can be used as an ideal therapeutic agent to manage Diabetic Peripheral neuropathy

A CLINICAL EFFICACY OF ZANTHOXYLUM RHETSA (ROXB.) DC IN SIRAJAGRANTHI (VARICOSE VEIN) – A CASE REPORT

Dr Veena Naik

GAMC MYSORE India.
Ayurveda, the holistic medicinal science has given us an ocean of treasure in knowing and treating the diseases for the welfare of mankind. Our Acharyas have used a lot of medicinal plants in treatment of various diseases either as single drug or in compound formulations. Varicose vein (sirajagranthi) become a day today problem particularly in middle aged and elderly people. Because of the long standing 10-20 % of the adult developed this disease. Hereditary factors, lifting heavy weight and high blood pressure are the other reason for developing it. Surgery is remedy for this condition. There are many medicinal plants mentioned in classics for various ailments. Apart from such references, the same plants or their source plants are used for some other diseases by the folklore practitioners since long period. Zanthoxylum rhetsa (Roxb.) DC. is one such source plant for the drug ‘Tumburu’ mentioned in Ayurveda for its utility in the diseases like Kushta, Shoola and Krimi. But, its use in Siraja Granthi is not mentioned in the Ayurvedic literature. The folklore practitioners of Dakshina Kannada District are successfully using the bark powder mixed with lemon juice as external application in case of varicose vein and so far, it is not explored scientifically. Such folk plants are needed to be re-validated scientifically. So, case report is conducted to study the efficacy of Zanthoxylum rhetsa (Roxb) DCtherapeutic efficacy in Siraja granthi (varicose vein) is undertaken and it has been proved significantly.

EFFICACY OF VIRECHANA IN THE MANAGEMENT OF PITTAJA SHIRASHOOLA – AN EVIDENT CASE REPORT

Dr Prabhu C Nagalapur

Shree Jagadguru Gavisiddeshwar Ayurvedic Medical College and Hospital, Koppal India.
Background: Generally Headaches are diagnosed as Shirashoola but not specific as per doshic predominance according to Ayurveda. The Chikitsa sutra, Virechana which is not administered in regular practice for Shirashoola was adopted accordingly in this case rather than only conservative management. Brief Case Report: Clinical diagnosis of Pittaja Shirashoola was made in a case of a 28-year-old male patient who presented with pain in all areas of the head, pain around the eyes and nose, sometimes blurred vision, giddiness associated with acid reflux, poor sleep, and anxiety. In the clinical finding elevated blood pressure was noted. Treatment for the case included deepana, pachana, virechana karma, and samsarjana krama. Discussion: Virechana medications stimulate cholinergic neurons and serotonergic receptors on cranial arteries, which reduce pain by inducing vasoconstriction and preventing excessive neuronal activity. Raktashodhana and pitta dosha prakopa is done by virechana due to ashraya aashrayi bhava. Since Sira is Dooshya and Upadhatu of Rakta Dhatu, Virechana may have assisted in lowering high blood pressure, which would have decreased Shirashoola. Conclusion: According to this case study, Virechana, treatment modality for pittaja shirashoola showed quick and marked reduction in the signs and symptoms as well as blood pressure and provided clinically substantial alleviation. KEY WORDS: Virechana, Shirashoola, Headache, Shodhana, Pittaja

Efficacy of Majoon Chobchini versus Majoon Ushba with Roghane Surkh in Post Chikungunya Arthritis - A Randomized Single Blind Comparative Clinical Trial

Prof (Dr). Mohd Aleemuddin Quamri, Aafreen Siddiqui, Md Anzar Alam

National Institute of Unani Medicine, Bengaluru
Background: Post Chikungunya Arthritis (PCA) is a prevalent and debilitating condition following Chikungunya fever, characterized by persistent arthralgia and joint-related symptoms. While conventional treatments include non-steroidal anti-inflammatory drugs (NSAIDs) and disease-modifying antirheumatic drugs (DMARDs), they are associated with various side effects. In Unani medicine, the use of Majoon Chobchini, Majoon Ushba, and Roghane Surkh has been recommended for PCA management, potentially offering a safer alternative. Methods: This randomized single-blind comparative clinical trial, conducted over one and a half years, involved 99 PCA patients aged 18-50 years. Patients were randomly assigned to either group A (Majoon Chobchini with Roghane Surkh) or group B (Majoon Ushba with Roghane Surkh). Disease activity and inflammatory markers were assessed using Disease Activity Score (DAS 28), Clinical Disease Activity Index (CDAI), Health Assessment Questionnaire (HAQ), and C - reactive protein (CRP) levels. Safety parameters including hematological and hepato and renal biochemical profiles were monitored. Statistical analysis was performed using appropriate tests. Results: Both Group A and Group B showed significant improvements in DAS 28 scores (p<0.001), HAQ scores (p<0.001), CDAI scores (p<0.001), and CRP levels (p<0.001) after the 4-week treatment, with no significant differences between the groups. Safety parameters remained stable, indicating the safety of both Majoon Chobchini and Majoon Ushba. Conclusion: Majoon Chobchini and Majoon Ushba with Roghane Surkh demonstrate comparable efficacy in reducing the symptoms of PCA, as evidenced by improvements in disease activity and inflammation parameters. Both interventions exhibited a favorable safety profile. These findings suggest the potential of these Unani formulations as alternative therapeutic options for PCA management, warranting further research and clinical exploration

Management of Pakshaghat (Stroke) through Panchakarma Therapies: A Case Report

Dr. Avvinish Narine, Dr. Anil Soni, Dr. Gopesh Mangal, Dr. Fatemeh Moazzamipeiro

Department of Maulik Siddhanta and Samhita, National Institute of Ayurveda (DU), Jaipur. India.
Need: Stroke is a leading cause of mortality and morbidity in India, with limited rehabilitation options. This study adds to the scientific literature by demonstrating the potential of Panchakarma therapies in stroke rehabilitation, highlighting a promising holistic strategy. Aim: To evaluate the effectiveness of Panchakarma therapies in managing Pakshaghat (stroke) and improving functional outcomes. Methodology: A 41-year-old male patient with Pakshaghat symptoms underwent six months of comprehensive Panchakarma therapy, including Rasa Aushadhi, Shashtika Shali Pinda Swedana, Mushtadi Yapana Basti, Shirodhara (Dashmoola Siddha Ksheera), and Nasya (Ksheerbaladi Taila). Result: Significant improvements were observed, with regained strength in the right upper and lower extremities and independent walking. This case report demonstrates the potential of Panchakarma therapies in stroke rehabilitation, offering a unique treatment protocol and exceptional outcome. Conclusion: Integrating Panchakarma therapies with modern medicine may provide a valuable adjunctive strategy for managing stroke, warranting further research. This case report highlights the need for exploring alternative approaches to stroke rehabilitation and the potential of Ayurveda in improving patient outcomes.
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